Findings of Research Misconduct

Notice is hereby given that ORI has taken final action in the following case:

Based on the report of an investigation conducted by UVA and additional analysis conducted by ORI in its oversight review, ORI found that Dr. Jayant Jagannathan, former Resident Physician at UVA Medical Center, engaged in research misconduct by including, in 5 publications, large amounts of text and an illustration that he plagiarized from publications supported by the following NIH grant awards: T32CA09677, P01HL024136, R01HL059157, P50CA090270, M01RR01346, R01CA075979, R01DK064169, R01NS027544, R01NS052406, and K08NS002197 and by intramural funds from the NINDS Surgical Neurosurgery Branch and from NIDCR.

Publications in which Respondent reported plagiarized material were:

1. Jagannathan, J., Li, J., Szerlip, N., Vortmeyer, A.O., Lonser, R.R., Oldfied, E.H., Zhuang, Z. “Application and implementation of selective tissue microdissection and proteomic profiling in neurological disease.’ Neurosurgery 64:4-14, 2009 (to be retracted);

2. Jagannathan, J., Prevedello, D.M., Dumont, A.S., Laws, E.R. “Cellular Signaling Molecules as Therapeutic Targets in the Treatment of Glioblastoma Multiforme.’ Neurosurgical Focus 20(4):E8, 2006 (retracted “due to plagiarism,’ Neurosurgical Focus 30(2):E8r, 2011);

3. Kanter, A.S., Jagannathan, J., Shaffrey, C.I., Ouellet, J.A., Mummaneni, P.V. “Inflammatory and dysplastic lesions involving the spine.’ Neurosurgical Clinics of North America 19(1):93-109, 2008;

4. Jagannathan, J., Dumont, A.S., Prevedello, D.M., Oskouian, R.J., Lopes, B., Jane, J.A. Jr, Laws, E.R. Jr. “Genetics of pituitary adenomas: Current theories and future implications.’ Neurosurgical Focus 19(5):E4, 2005 (retracted “due to plagiarism,’ Neurosurgical Focus 30(2):E4r, 2011);

5. Jagannathan, J. “Role of calcium influx and modulation of local neurotransmitters as hallmarks of pediatric traumatic brain injury.’ Biomarkers Med. 3:95-97, 2009 (retracted online 9/11/ 2010).

Dr. Jagannathan has entered into a Voluntary Settlement Agreement (Agreement) and has voluntarily agreed for a period of 4 years, beginning on October 20, 2011:

(1) To have his research supervised; Respondent agreed to ensure that prior to the submission of an application for U.S. PHS support for a research project on which his participation is proposed and prior to his participation in any capacity on PHS-supported research, the institution employing him must submit a plan for supervision of his duties to ORI for approval; the plan for supervision must be designed to ensure the scientific integrity of his research contribution; Respondent agreed that he will not participate in any PHS-supported research after 60 days from the effective date of the Agreement until a plan for supervision is submitted to and approved by ORI; Respondent agreed to maintain responsibility for compliance with the agreed upon supervision plan;

(2) That any institution employing him must submit, in conjunction with each application for PHS funds, or report, manuscript, or abstract involving PHS-supported research in which Respondent is involved, a certification to ORI that the data provided by Respondent are based on actual experiments or are otherwise legitimately derived and that the data, procedures, and methodology are accurately reported in the application, report, manuscript, or abstract;

(3) To submit a letter to the journal editor for publication 3 (Neurosurgical Clinics of North America) listed above, requesting that the paper be retracted because Respondent had plagiarized portions of text reported in it; the letter must be sent to ORI for approval prior to being sent to the editor; and

(4) To exclude himself from serving in any advisory capacity to PHS including, but not limited to, service on any PHS advisory committee, board, and/or peer review committee, or as a consultant.

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