More ARRA Largesse

NIH Director’s Opportunity for Research in Five Thematic Areas (RC4)

NIH-wide

LOI Due Date: February 15, 2010
Application Due Date: March 15, 2010

This program will support projects that address research endeavors in specific areas that will benefit from significant 3-year funds (at least $1.5M in total costs) without the expectation of continued NIH funding beyond this period. The research supported by the program should have high short-term impact, and a high likelihood of enabling growth and investment in biomedical research and development, public health, and health care delivery. ($80M committed)

Applicants must propose (customized 12-p Research Strategy) to develop and implement critical research innovations in one or more of these 5 thematic areas:

Applying Genomics and Other High Throughput Technologies
Translating Basic Science Discoveries into New and Better Treatments
Using Science to Enable Health Care Reform
Focusing on Global Health
Reinvigorating the Biomedical Research Community

Program officers listed by participating IC.

***

Methodology Development in Comparative Effectiveness Research (RC4)

NHLBI, NCI, NIBIB, NIDDK, NINDS, NLM, NIA, NIAAA

No LOI, Application Due Date: February 26, 2010

Total costs cannot exceed $1.5M for 3-year project period … 6-7 awards to be made … standard 12-p Research Strategy

This FOA solicits applications for projects proposing innovative approaches to enhance, develop, or evaluate methodologies to improve the efficiency, validity, and credibility of CER studies. Broad areas of methodology research include (but are not limited to) control for confounding and bias in observational studies, systematic combination of data from randomized and observational studies to streamline comparative assessments, linkage and use large amounts of data derived from practice-based warehouses, health economics, decision analysis, altered treatment effects in the setting of multiple comorbidities, value-of-information research and CER simulations, robust sub-group or personalized treatment interactions, rapid roll-out of observational studies and pragmatic trials within integrated health care systems or existing large-scale registries, use of Internet platforms to perform mega-randomized trials at low cost, and innovative approaches for rapid and efficient design, implementation, and completion of large-scale pragmatic trials and implementation studies, including Bayesian, adaptive, and cluster designs.

When appropriate, this FOA encourages investigators to produce publicly available CER tools, such as software, computerized trial algorithms, and web tools for study management.

Scientific/Research Contact:
Michael S. Lauer, MD
Division of Cardiovascular Sciences, NHLBI
Telephone: (301) 435-0422
Email: lauerm@nhlbi.nih.gov

***

Comparative Effectiveness Research on Upper Endoscopy in Gastroesophageal Reflux Disease (GERD), Eradication Methods for Methicillin Resistant Staphylococcus aureus (MRSA), and Dementia Detection and Management Strategies (RC4)

NIA, NIAID, NIDDK, NIMH

No LOI, Application Due Date: February 26, 2010

Total costs cannot exceed $1.25M for a 3-year project period … 3-4 awards are expected per research area … standard 12-p Research Strategy narrative

This FOA solicits applications for small, 3-year projects proposing analyses of archival or administrative datasets, pilot clinical trials, observational studies, planning of future definitive research protocols, building of research networks or registries, or demonstration projects from multidisciplinary teams with relevant expertise to conduct CER studies of upper endoscopy in GERD, MRSA eradication methods, or dementia detection and management strategies. The research proposed must address the IOM recommendation for studies in the selected area. (more details on each in RFA)

Program contacts by research area

***

Behavioral Economics for Nudging the Implementation of Comparative Effectiveness Research: Pilot Research (RC4)

AHRQ, NIA, NIMH, NINDS, NINR, NIDA

No LOI, Application Due Date: March 19, 2010

Total costs cannot exceed $1.25M for the 3-year project period … 4-5 awards are anticipated … standard 12-p Research Strategy narrative

This FOA solicits applications for pilot clinical trials, observational studies, or demonstration projects from multidisciplinary teams with relevant expertise in behavioral economics, psychology, and health services targeting the uptake of specific, previously identified CER. Broad areas of problematic uptake include (but are not limited to) the prescription of comparatively more effective medications or procedures where not directly counter-indicated, failures to schedule or execute indicated screening tests (which also clearly have a patient component), inadequate post-procedure follow-up assessment, failure to adopt education programs to educate patients about effective options (such as smoking cessation after AMI, weight loss programs for the obese, etc.), failure to use new management technologies (such as electronic medical records), and failure to adopt new training methods (such as surgery simulators, residents working past the recommended 16-hour limit for shifts without naps, etc.). Applicants must provide a rationale for the specific behavioral economic methods they propose to evaluate, and demonstrate how they differ from currently implemented P4P methods.

Scientific/Research Contacts:

Jonathan W. King, Ph.D.
Division of Behavioral and Social Research, NIA
Telephone: (301) 402-4156
Email: kingjo@nia.nih.gov

Bill Encinosa, Ph.D.
Center for Delivery, Organization and Markets, AHRQ
Telephone: 301-427-1437
Email: William.encinosa@ahrq.hhs.gov

***

Behavioral Economics for Nudging the Implementation of Comparative Effectiveness Research: Clinical Trials (RC4)

AHRQ, NIA, NIMH, NINDS, NINR, NIDA

No LOI, Application Due Date: April 7, 2010

Total costs cannot exceed $7.5M for the 3-year project period … 2 awards are anticipated … standard 12-p Research Strategy narrative

This FOA solicits applications for large-scale, multi-site, 3-year projects proposing randomized clinical trials (RCTs), cluster randomized trials (CRTs), or other robust randomized trial designs from multidisciplinary teams with relevant expertise in behavioral economics, psychology, epidemiology, clinical and health services research targeting the uptake of specific, previously identified CER. Broad areas of problematic uptake include (but are not limited to) the prescription of comparatively more effective medications or procedures where not directly counter-indicated, failures to schedule or execute indicated screening tests (which also clearly have a patient component), inadequate post-procedure follow-up assessment, failure to adopt education programs to educate patients about effective options (such as smoking cessation after AMI, weight loss programs for the obese, etc.), failure to use new management technologies (such as electronic medical records), and failure to adopt new training methods (such as surgery simulators, residents working past the recommended 16-hour limit for shifts without naps, etc.). Applicants must provide a rationale for the specific behavioral economic methods they propose to evaluate, and demonstrate how they differ from currently implemented P4P methods.

Scientific/Research Contacts:

Jonathan W. King, Ph.D.
Division of Behavioral and Social Research, NIA
Telephone: (301) 402-4156
Email: kingjo@nia.nih.gov

Bill Encinosa, Ph.D.
Center for Delivery, Organization and Markets, AHRQ
Telephone: 301-427-1437
Email: William.encinosa@ahrq.hhs.gov

2 Comments »

  1. I want a grant for behavioral economic nudges to my fucking nut sack.

  2. BB said

    I just want nudges to my funding.

RSS feed for comments on this post · TrackBack URI

Leave a Reply

Fill in your details below or click an icon to log in:

WordPress.com Logo

You are commenting using your WordPress.com account. Log Out / Change )

Twitter picture

You are commenting using your Twitter account. Log Out / Change )

Facebook photo

You are commenting using your Facebook account. Log Out / Change )

Google+ photo

You are commenting using your Google+ account. Log Out / Change )

Connecting to %s

%d bloggers like this: